Acute kidney injury

NATTHA PRAMONG, M.D.

Acute kidney injury is a group of symptoms characterized by a rapid decline in kidney function within hours or days, typically not exceeding 7 days. The main causes are shock or low blood pressure, leading to the accumulation of waste products in the blood, abnormalities in minerals and fluids in the body, and a reduced immune response. Prompt and appropriate diagnosis and care can help the kidneys return to normal function.


Symptoms of acute kidney injury:

  • Decreased urine output: Some individuals may not urinate at all, or urinate less than 400 milliliters per day.
  • Swelling of the arms and legs.
  • Easy fatigue and weakness, even without exertion.
  • Nausea and vomiting.
  • Confusion and lethargy.

Causes of acute kidney injury:

  • Decreased fluid volume in the body: such as from severe diarrhea, significant blood loss from gastrointestinal bleeding or internal organs, or sudden blood loss from trauma.
  • Sudden low or high blood pressure.
  • Medications or toxins, including dietary supplements and herbal remedies.
  • Acute glomerulonephritis, caused by medications, infections, or autoimmune disorders attacking kidney tissue.
  • Obstruction of the urinary tract, such as from kidney stones, enlarged prostate gland, or bilateral kidney swelling.
  • Infection in the bloodstream.

Treatment:

  • Address the underlying cause, such as discontinuing medications that may be causing the issue and ensuring adequate hydration in cases of fluid deficit or shock.
  • Control blood pressure to normal levels.
  • Avoid nephrotoxic substances and adjust medication dosages accordingly.
  • Manage with renal replacement therapy in cases where the kidneys are unable to function properly, especially if there are severe electrolyte imbalances or pulmonary edema.

26 Dec, 2023

NATTHA PRAMONG, M.D.

Specialties
Nephrology Geriatrics

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